| Description | PI3K-IN-41 (compound 2), a photocaged PI3K inhibitor (IC50=18.92 nM) with anticancer properties, demonstrates potent PI3K inhibition following UV light irradiation and has been shown to enhance antitumor effects [1]. This compound has potential for use in precisely controlled cancer therapeutics. |
| In vitro | PI3K-IN-41（化合物2）（10 nM）能够减少HGC-27细胞内AKT磷酸化水平，并在紫外线照射5分钟、15分钟及30分钟后，以（1-10 μM）的浓度显著抑制HGC-27细胞集落形成[1]。 |
| molecular weight | 911.88 |
| Molecular formula | C45H39F2N5O12S |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |