| Description | PI3K-IN-38 is an orally available and potent PI3K inhibitor with an IC50 value of 0.541 µM for PI3K-α. PI3K-IN-38 exhibits anticancer and anti-inflammatory activity and inhibits tumor growth in vivo. |
| Target activity | p110α:0.541 μM |
| molecular weight | 380.44 |
| Molecular formula | C20H24N6O2 |
| CAS | 1382979-64-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/mL (157.71 mM) |
| References | 1. Dotson J, et al. Tricyclic pi3k inhibitor compounds and methods of use. WO2012082997A1. |