| Description | Physostigmine is a potent and reversible inhibitor of cholinesterase. It is also reported to form a slowly degrading carbamylated enzyme complex with acetylcholinesterase (AChE). |
| Synonyms | Physostol, Antilirium, Eserine, 毒扁豆碱, Esromiotin, Ezerin |
| molecular weight | 275.35 |
| Molecular formula | C15H21N3O2 |
| CAS | 57-47-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: Soluble H2O: Insoluble |
| References | 1. Glatstein MM, Alabdulrazzaq F, Garcia-Bournissen F, Scolnik D. Use of physostigmine for hallucinogenic plant poisoning in a teenager: case report and review of the literature. Am J Ther. 2012 Sep;19(5):384-8. doi: 10.1097/MJT.0b013e3181f0cbb4. Review. PubMed PMID: 20861718. 2. Frascogna N. Physostigmine: is there a role for this antidote in pediatric poisonings? Curr Opin Pediatr. 2007 Apr;19(2):201-5. Review. PubMed PMID: 17496766. 3. Allen L, Alsalim W. Best evidence topic report. Gammahydroxybutyrate overdose and physostigmine. Emerg Med J. 2006 Apr;23(4):300-1. Review. PubMed PMID: 16549578; PubMed Central PMCID: PMC2579509. 4. Traub SJ, Nelson LS, Hoffman RS. Physostigmine as a treatment for gamma-hydroxybutyrate toxicity: a review. J Toxicol Clin Toxicol. 2002;40(6):781-7. Review. PubMed PMID: 12475191. |