| Description | Physcion (Physcione) (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively. Physcion (Parietin) exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects. |
| In vivo | Physcion可改变防御相关基因的表达,并使大麦叶中叶子特有的硫素表达增强,从而控制白粉病。 |
| Target activity | 6-phosphogluconate dehydrogenase:38.5 μM |
| Synonyms | 大黄素甲醚, Physcione, Parietin, Rheochrysidin |
| molecular weight | 284.26 |
| Molecular formula | C16H12O5 |
| CAS | 521-61-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: Insoluble DMSO: Insoluble |
| References | 1. Ma X, et al. Pest Manag Sci, 2010, 66(7), 718-724. |