| Description | Phosphatidylcholines (PC) are a class of phospholipids that incorporate choline as a headgroup. They are a major component of biological membranes and can be easily obtained from a variety of readily available sources, such as egg yolk or soybeans, from which they are mechanically or chemically extracted using hexane. They are also a member of the lecithin group of yellow-brownish fatty substances occurring in animal and plant tissues. Dipalmitoyl phosphatidylcholine (aka: lecithin) is a major component of pulmonary surfactant and is often used in the L/S ratio to calculate fetal lung maturity. While phosphatidylcholines are found in all plant and animal cells, they are absent in the membranes of most bacteria, including Escherichia coli. Purified phosphatidylcholine is produced commercially. |
| Synonyms | Azolectin, PC. Phosphatidyl choline, L-α-Lecithin |
| molecular weight | 760.08 |
| Molecular formula | C42H82NO8P |
| CAS | 8057-53-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Miñones J, Muñoz M, Miñones Trillo J, Haro I, Busquets MA, Alsina Esteller MA. Miscibility and Langmuir studies of the interaction of E2 (279-298) peptide sequence of Hepatitis G Virus/GB Virus-C with Dipalmitoyl Phosphatidyl Choline and Dimiristoyl Phosphatidyl Choline phospholipids. Langmuir. 2015 Jul 10. [Epub ahead of print] PubMed PMID: 26161460. 2. Saini RK, Dube A, Gupta PK, Das K. Diffusion of chlorin-p6 across phosphatidyl choline liposome bilayer probed by second harmonic generation. J Phys Chem B. 2012 Apr 12;116(14):4199-205. doi: 10.1021/jp205335z. Epub 2012 Mar 29. PubMed PMID: 22414064. 3. Toimil P, Prieto G, Miñones J Jr, Trillo JM, Sarmiento F. Monolayer and Brewster angle microscopy study of human serum albumin-dipalmitoyl phosphatidyl choline mixtures at the air-water interface. Colloids Surf B Biointerfaces. 2012 Apr 1;92:64-73. doi: 10.1016/j.colsurfb.2011.11.022. Epub 2011 Nov 20. PubMed PMID: 22154096. 4. Gupta NK, Dixit VK. Bioavailability enhancement of curcumin by complexation with phosphatidyl choline. J Pharm Sci. 2011 May;100(5):1987-95. doi: 10.1002/jps.22393. Epub 2010 Nov 24. PubMed PMID: 21374628. |
Phosphatidyl choline (from egg yolk)
CAS No.: 8057-53-2
Phosphatidylcholines (PC) are a class of phospholipids that incorporate choline as a headgroup. They are a major compone
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