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PHI-101

CAS No.: 2127107-15-5

PHI-101 is an orally available and selective checkpoint kinase 2 (Chk2) inhibitor for the study of refractory acute myel
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Description PHI-101 is an orally available and selective checkpoint kinase 2 (Chk2) inhibitor for the study of refractory acute myelogenous leukemia (AML) and ovarian cancer.
Synonyms PHI101, PHI 101
molecular weight 386.44
Molecular formula C19H19FN4O2S
CAS 2127107-15-5
Storage store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 80 mg/mL (207.02 mM), Sonication is recommended.
References 1. Nam K Y, et al. PHI-101 Is a Potent Third-Generation FLT3 Inhibitor Developed to Overcome Resistance in Acute Myeloid Leukemia[J]. Blood, 2020, 136: 28.