| Description | Phenyltoloxamine (Bistrimin) is an antihistamine agent with sedative and analgesic effects. Phenyltoloxamine also has potent Sigma-1 receptor binding affinity with Ki of 160 nM [1] [2] [3]. |
| In vitro | Phenyltoloxamine (10-50 μM, 24 h) exhibits cytotoxicity in EVSA-T cells [2]. Phenyltoloxamine exhibits potent Sigma 1 Receptor (S1R) binding affinity with a K i value of 160 nM [3]. Phenyltoloxamine (100 μM) inhibits human liver macrosaml CYP2D6 enzyme by 99.0% [4]. |
| molecular weight | 255.35 |
| Molecular formula | C17H21NO |
| CAS | 92-12-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |