| Description | 5-Phenylhydantoin (5-Phenylhydantoin) is a metabolite of Mephenytoin. 5-Phenylhydantoin has been shown to bind to voltage-dependent sodium channels (NVSC) and has anti-epileptic properties. |
| Synonyms | 5-苯基海因, 5-Phenylhydantoin |
| molecular weight | 176.17 |
| Molecular formula | C9H8N2O2 |
| CAS | 89-24-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 30 mg/mL (170.29 mM) |
| References | 1. Maguire JH, Hypolipidemic activity of antiepileptic 5-phenylhydantoins in mice. Eur J Pharmacol. 1985 Oct 29;117(1):135-8. 2. Brown ML, et al. Effects of log P and phenyl ring conformation on the binding of 5-phenylhydantoins to the voltage-dependent sodium channel. J Med Chem. 1997 Feb 14;40(4):602-7. 3. Serra R, et al. J Inflamm (Lond). 2010 Sep 15;7:48. |