| Description | PGD2-IN-1 (PGD2-inhibitor) is an effective DP receptor antagonist (IC50:0.3 nM), a compound that can inhibit prostaglandin D2 (PGD2) signaling. PGD2-IN-1 specifically targets and regulates the activity of PGD2 receptors or enzymes involved IN PGD2 synthesis or metabolism. |
| Target activity | DP:0.3 nM. |
| Synonyms | PGD2-inhibitor |
| molecular weight | 460.35 |
| Molecular formula | C23H23Cl2N3O3 |
| CAS | 885066-67-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 45 mg/mL (97.75 mM), Sonication is recommended. |
| References | 1. Mu L, et al. Understanding DP receptor antagonism using a CoMSIA approach. Bioorg Med Chem Lett. 2011 Jan 1;21(1):66-75. 2. Patent: WO/2006/044732A2 |