| Description | PF-06679142 is an effective AMPK activator. PF-06679142 exhibited robust activation of AMPK in rat kidneys as well as desirable oral absorption. |
| Synonyms | PF06679142, PF-6679142, PF6679142, PF 6679142 |
| molecular weight | 357.35 |
| Molecular formula | C20H17F2NO3 |
| CAS | 1467059-66-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Edmonds DJ, Kung DW, Kalgutkar AS, et al. Optimization of Metabolic and Renal Clearance in a Series of Indole Acid Direct Activators of 5'-Adenosine Monophosphate-Activated Protein Kinase (AMPK). J Med Chem. 2018 Feb 28. doi: 10.1021/acs.jmedchem.7b01641. [Epub ahead of print] PubMed PMID: 29466005. |