| Description | PF-02367982 is a potent, selective nonsteroidal progesterone antagonist. |
| Synonyms | PF 02367982 |
| molecular weight | 336.39 |
| Molecular formula | C19H20N4O2 |
| CAS | 913344-84-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Schmidt C, Klammt J, Thome UH, Laube M. The interaction of glucocorticoids and progesterone distinctively affects epithelial sodium transport. Lung. 2014 Dec;192(6):935-46. doi: 10.1007/s00408-014-9640-3. Epub 2014 Aug 31. PubMed PMID: 25173779. 2. de Giorgio-Miller A, Bungay P, Tutt M, Owen J, Goodwin D, Pullen N. The translational pharmacology of a novel, potent, and selective nonsteroidal progesterone receptor antagonist, 2-[4-(4-cyano-phenoxy)-3,5-dicyclopropyl-1H-pyrazol-1-yl]-N-methylacetamide (PF-02367982). J Pharmacol Exp Ther. 2008 Oct;327(1):78-87. doi: 10.1124/jpet.108.140467. Epub 2008 Jul 1. PubMed PMID: 18593954. |