| Description | PEX5-PEX14 PPI-IN-1 (Compound 8) is a PEX14-PEX5 protein-protein interaction (PPI) inhibitor that disrupts the interaction between PEX5 and TbPEX14 with an inhibitory constant (Ki) of 53 μM. It effectively inhibits the bloodstream form of Trypanosoma brucei brucei, with a half-maximal effective concentration (EC50) of 5 μM [1]. |
| molecular weight | 444.53 |
| Molecular formula | C26H28N4O3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |