| Description | Pentamidine dimesylate is an inhibitor of calcium-dependent complex formation with p53 [(Ca)S100B-p53) in malignant melanoma (MM). Pentamidine dimesylate restores p53 tumor suppressor activity in vivo. |
| molecular weight | 436.53 |
| Molecular formula | C20H28N4O5S |
| CAS | 6823-79-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Bronner U, Doua F, Ericsson O, Gustafsson LL, Miézan TW, Rais M, Rombo L. Pentamidine concentrations in plasma, whole blood and cerebrospinal fluid during treatment of Trypanosoma gambiense infection in Côte d'Ivoire. Trans R Soc Trop Med Hyg. 1991 Sep-Oct;85(5):608-11. PubMed PMID: 1780988. |