| Description | Penicillin G potassium (Benzylpenicillin potassium) is the potassium salt form of penicillin G, a broad-spectrum penicillin antibiotic. |
| In vivo | Penicillin G potassium 通过饮水给药，能有效降低由S. suis感染引起的死亡率，并减少可能导致疾病及成为猪对猪传播感染源的S. suis的扁桃体携带[1]。 |
| Animal experiments | Fresh stock solution was prepared twice daily by an individual who was not involved with assessment of the study pigs. The test article was administered via the drinking water for 5 d over 2 periods of treatment. The first treatment period commenced on the day of weaning, when the pigs were moved into the nursery barns (Day 1) and ended on Day 5. The second treatment period began on Day 21 and ended on Day 25. The Control group did not receive treatment[1]. |
| Synonyms | 青霉素钾, Benzylpenicillin potassium |
| molecular weight | 372.48 |
| Molecular formula | C16H17KN2O4S |
| CAS | 113-98-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: 80 mg/mL (214.7 mM), Sonication is recommended. DMSO: 200 mg/mL (536.9 mM), Sonication is recommended. |
| References | 1. Byra C , Gadbois P , Cox W R , et al. Decreased mortality of weaned pigs with Streptococcus suis with the use of in-water potassium penicillin G[J]. Canadian Veterinary Journal, 2011, 52(3):272. 2. Roussel A J , Hooper R N , Cohen N D , et al. Evaluation of the effects of penicillin G potassium and potassium chloride on the motility of the large intestine in horses[J]. American Journal of Veterinary Research, 2003, 64(11):1360-1363. |