| Description | PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells. It promotes mitochondrial bioenergetics, reduces glycolytic activity, and triggers apoptosis via the mitochondrial pathway. Additionally, PDK-IN-2 has been shown to impede tumor growth in a 4T1 syngeneic mouse model [1]. |
| molecular weight | 497.33 |
| Molecular formula | C17H23AsCl2N2O2S2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |