| Description | PDE4-IN-5 (compound 33a) is a highly potent and selective inhibitor of the enzyme PDE4, with an IC50 value of 3.1 nM. It exhibits excellent skin permeability and its binding mechanism has been extensively characterized. Additionally, PDE4-IN-5 demonstrates a notable anti-psoriasis effect [1]. |
| molecular weight | 356.46 |
| Molecular formula | C21H28N2O3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |