| Description | PDE4-IN-4 is a compound acting as both a potent M3 antagonist (p IC 50 = 10.2) and a PDE4 inhibitor (p IC 50 = 8.8), designed for inhalation-based treatment of pulmonary diseases. |
| Synonyms | PDE4-IN-4 |
| molecular weight | 726.67 |
| Molecular formula | C36H37Cl2N3O7S |
| CAS | 1793069-00-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Armani E, et al. Discovery of M3 Antagonist-PDE4 Inhibitor Dual Pharmacology Molecules for the Treatment of Chronic Obstructive Pulmonary Disease. J Med Chem. 2021 Jul 8;64(13):9100-9119. |