| Description | PBS-1086 is a novel dual inhibitor of the canonical and noncanonical NF-κB pathways, increasing the magnitude and duration of initial EGFR inhibitor response in multiple NSCLC models, decreasing PDHK1 expression, and suppressing phosphorylation of the PDHK1 protein substrate PDHA1 in a panel of PTEN-deficient cell lines. |
| molecular weight | 312.28 |
| Molecular formula | C16H12N2O5 |
| CAS | 1246668-32-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |