| Description | Acid blue is a dark bluish synthetic triphenylmethane dye. It used as a food coloring. The color of the dye is pH-dependent. The structure is also redox-sensitive, changing from a reduced yellow form to an oxidized red form in solution. It is usable as a reversible redox indicator in some analytical methods. |
| Synonyms | Acid blue 3, L-Blau 3, Food Blue 3, Blue ZN 3, NSC 5010, C.I. 42051 |
| molecular weight | 1159.42 |
| Molecular formula | C54H62CaN4O14S4 |
| CAS | 3536-49-0 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: Soluble |
| References | 1. Langner-Viviani F, Chappuis S, Bergmann MM, Ribi C. [Anaphylaxis to blue dyes]. Rev Med Suisse. 2014 Apr 16;10(426):876-80. French. PubMed PMID: 24834647. 2. Giansanti F, Schiavone N, Papucci L, Bitossi A, Andreucci E, Pontenani F, Cutrì M, Menchini U. Safety testing of blue vital dyes using cell culture models. J Ocul Pharmacol Ther. 2014 Jun;30(5):406-12. doi: 10.1089/jop.2013.0213. Epub 2014 Feb 7. PubMed PMID: 24506324. 3. Ang CH, Tan MY, Teo C, Seah DW, Chen JC, Chan MY, Tan EY. Blue dye is sufficient for sentinel lymph node biopsy in breast cancer. Br J Surg. 2014 Mar;101(4):383-9; discussion 389. doi: 10.1002/bjs.9390. Epub 2014 Feb 3. PubMed PMID: 24492989. 4. Guo W, Zhang L, Ji J, Gao W, Liu J, Tong M. Evaluation of the benefit of using blue dye in addition to indocyanine green fluorescence for sentinel lymph node biopsy in patients with breast cancer. World J Surg Oncol. 2014 Sep 20;12:290. doi: 10.1186/1477-7819-12-290. PubMed PMID: 25239029; PubMed Central PMCID: PMC4182872. |