| Description | Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression. |
| molecular weight | 329.37 |
| Molecular formula | C19H20FNO3 |
| CAS | 61869-08-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/mL (182.17 mM) |
| References | 1. Cipriani A , Furukawa T A , Veronese A , et al. Paroxetine versus other anti-depressive agents for depression[J]. Cochrane Database of Systematic Reviews, 2007. 2. Anick Bérard, Iessa N , Chaabane S , et al. The risk of major cardiac malformations associated with paroxetine use during the first trimester of pregnancy: a systematic review and meta‐analysis[J]. Br J Clin Pharmacol, 2016, 81(4). |
| Citations | 1. Cai X M, Sun X Y, Li R, et al.The hippocampal Salt-Inducible Kinase 2-CREB-Regulated Transcription Co-activator 1 system mediates the antidepressant actions of paroxetine in mice.Behavioural Brain Research.2024: 114972. |