| Description | Palifosfamide (tromethamine), a synthetically derived alkylating agent, exhibits potential antineoplastic properties. Acting as the stabilized active metabolite of ifosfamide, it irreversibly alkylates and crosslinks DNA at GC base pairs, inhibiting DNA replication and inducing cell death. Palifosfamide (tromethamine) boasts reduced toxicity in comparison to ifosfamide. |
| Synonyms | IPM tromethamine, Isophosphoramide mustard tromethamine, ZIO-201 tromethamine, Isophosphoramide mustard tromethamine ; IPM tromethamine ; ZIO-201 tromethamine |
| molecular weight | 342.16 |
| Molecular formula | C8H22Cl2N3O5P |
| CAS | 1070409-31-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |