| Description | Palbociclib (PD 0332991) dihydrochloride is an orally active, selective inhibitor of CDK4 (IC50: 11 nM) and CDK6 (IC50: 16 nM). Palbociclib dihydrochloride has anti-proliferative activity and cell cycle arrest in HR-positive and HER2-negative breast cancers, as well as in hepatocellular carcinoma studies. |
| molecular weight | 520.45 |
| Molecular formula | C24H31Cl2N7O2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |