| Description | P-gp Inhibitor 15 (compound 7a), a nonsubstrate inhibitor of P-glycoprotein (Pgp), inhibits Pgp-ATPase activity and interferes with Pgp-mediated Rhodamine123 efflux. Additionally, this compound enhances the inhibitory effect of Paclitaxel on tumor progression in the KBV xenograft tumor model in nude mice [1]. |
| molecular weight | 572.86 |
| Molecular formula | C35H60N2O4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |