| Description | P-gp/BCRP-IN-2 (compound 15), an oxadiazole derivative, functions as a dual inhibitor targeting both the ABC transporter P-glycoprotein (IC50: 1.6 nM) and BCRP (IC50: 600 nM). Additionally, it bolsters the anti-proliferative impact of Doxorubicin in the drug-resistant HT29/DX and MDCK-MDR1 human adenocarcinoma colon cancer cell lines [1]. |
| molecular weight | 557.64 |
| Molecular formula | C32H35N3O6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |