| Description | Oxybuprocaine is an ester-type local anesthetic that is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. |
| Synonyms | Butoxyprocaine, BNX, Benoxinate, Novescine, Novesin |
| molecular weight | 308.42 |
| Molecular formula | C17H28N2O3 |
| CAS | 99-43-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Little WB, Jean GS, Sithole F, Little E, Jean KY. Degree of corneal anaesthesia after topical application of 0.4% oxybuprocaine hydrochloride and 0.5% proparacaine hydrochloride ophthalmic solution in clinically normal cattle. Aust Vet J. 2016 Jun;94(6):181-5. doi: 10.1111/avj.12443. PubMed PMID: 27237118. 2. Giudici V, Baeza S, Douet JY, Regnier A. Corneal anesthesia following application of 0.4% oxybuprocaine hydrochloride ophthalmic solution to normal feline eyes. Vet Ophthalmol. 2015 Mar;18(2):141-6. doi: 10.1111/vop.12179. Epub 2014 May 14. PubMed PMID: 24824864. 3. Fernandez-Garcia P, Cerviño A, Quiles-Guiñau L, Albarran-Diego C, Garcia-Lazaro S, Sanchis-Gimeno JA. Corneal thickness differences between sexes after oxybuprocaine eye drops. Optom Vis Sci. 2015 Jan;92(1):89-94. doi: 10.1097/OPX.0000000000000449. PubMed PMID: 25360701. 4. Douet JY, Michel J, Regnier A. Degree and duration of corneal anesthesia after topical application of 0.4% oxybuprocaine hydrochloride ophthalmic solution in ophthalmically normal dogs. Am J Vet Res. 2013 Oct;74(10):1321-6. doi: 10.2460/ajvr.74.10.1321. PubMed PMID: 24066916. |