| Description | OU749 is a γ-glutamyl transferase (GGT) inhibitor with an intrinsic Ki of 17.6 μM. |
| Target activity | GGTase I:17.6 μM(Ki) |
| molecular weight | 361.44 |
| Molecular formula | C16H15N3O3S2 |
| CAS | 519170-13-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (138.34 mM) |
| References | 1. Wang L, et al. Fighting against drug-resistant tumors by the inhibition of γ-glutamyl transferase with supramolecular platinum prodrug nano-assemblies. J Mater Chem B. 2021 Jun 2;9(22):4587-4595. 2. King JB, et al. A novel, species-specific class of uncompetitive inhibitors of gamma-glutamyl transpeptidase. J Biol Chem. 2009 Apr 3;284(14):9059-65. |