| Description | ONO-RS-082 is a Ca2+-independent phospholipase A2 inhibitor. |
| In vitro | ONO-RS-082在3.5 μM的浓度下能够抑制人类血小板中由肾上腺素刺激产生的血栓素生成。此外，ONO-RS-082还能干扰内体管状结构的形成和高尔基复合体的维持[1]。 |
| molecular weight | 371.86 |
| Molecular formula | C21H22ClNO3 |
| CAS | 99754-06-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 30 mg/mL (80.67 mM) |
| References | 1. Banga H S , Simons E R , Brass L F , et al. Activation of phospholipases A and C in human platelets exposed to epinephrine: role of glycoproteins IIb/IIIa and dual role of epinephrine[J]. Proceedings of the National Academy of Sciences, 1986, 83(23):9197-9201. |