| Description | ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.028 μM for DYRK2, 0.05 μM and 0.005 μM for CK2α1 and CK2α2, and 0.005 μM for TNIK, respectively. This compound exhibits antitumor activity [1]. |
| Target activity | DYRK2:0.028 μM, DYRK1A:0.016 μM, DYRK1B:0.007 μM, CK2α2:0.005 μM, CK2α1:0.05 μM |
| molecular weight | 537.39 |
| Molecular formula | C22H14Cl2N2O6S2 |
| CAS | 1585246-23-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |