| Description | Oleonuezhenide is a natural product from Chinese formula Ligustrum lucidum, exerts neuroprotective effects and also considered as treatment of osteoporosis. |
| In vitro | Oleonuezhenide通过提高酪蛋白激酶2-α（CK2α）表达，促进β-连环蛋白和Runx2的核内转位。Oleonuezhenide通过缓解Wedelolactone引起的细胞毒性，保护骨髓间充质干细胞，并保持成骨细胞活性。 |
| In vivo | 在去卵巢小鼠中，通过增强成骨细胞活性，wedelolactone和oleonuezhenide的给予防止了去卵巢术引起的骨质流失。 |
| molecular weight | 1073.01 |
| Molecular formula | C48H64O27 |
| CAS | 112693-21-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Deng X, et al. The combined effect of oleonuezhenide and wedelolactone on proliferation and osteoblastogenesis of bone marrow mesenchymal stem cells. Phytomedicine. 2019 Dec;65:153103. 2. Sang H S, et al. A new neuroprotective compound of Ligustrum japonicum leaves.[J]. Planta Medica, 2006, 72(1):62-64. |