| Description | OGG1-IN-08 (OGG1-IN-O8) is an inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1;IC50 : 0.35 μM) |
| In vitro | OGG1-IN-O8 在50 μM浓度下，对OGG1具有选择性，明显优于其对Nei-like DNA glycosylase 1 (NEIL1)、endonuclease III homolog 1 (NTH1) 和formamidopyrimidine DNA glycosylase (Fpg) 的选择性。 |
| Target activity | OGG1:0.35 µM |
| Synonyms | OGG1-IN-O8 |
| molecular weight | 261.13 |
| Molecular formula | C9H6Cl2N2OS |
| CAS | 350997-39-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 27.5 mg/mL (105.32 mM) |
| References | 1. Lloyd, R.S., Mccullough, A.K., and Donley, N. Small molecule inhibitors of 8-oxoguanine DNA glycosylase-1 (OGG1). (2016). |