| Description | 1. Octyl Gallate is an antioxidant approved by the US Food and Drug Administration (FDA) as a food additive. 2. Octyl Gallate has antimetastatic activity. 3. Octyl Gallate shows antimicrobial activity against H. pylori, with a minimum inhibitory concentration (MIC) value of 125 ug/mL. 4. Combination therapy with octyl gallate and ferulic acid improves cognition and neurodegeneration in a transgenic mouse model of Alzheimer's disease.5. Octyl Gallate is a potential anticancer agent, it exhibited decreased MCF-7 & MDA-MB-231 survival and induced apoptosis, with IC50 value of 40 uM. 6. Octyl gallate (Octyl 3,4,5-trihydroxybenzoate) has antiviral activity, it shows an inhibitory effect on the growth of herpes simplex virus type 1 (HSV-1) in HEp-2 or Vero cells. 7. Octyl gallate shows antifungal activity against Saccharomyces cerevisiae ATCC7754 and Zygosaccharomyces bailii ATCC 60483. |
| Synonyms | Gallic acid octyl ester, n-Octylgallate, Octyl 3,4,5-trihydroxybenzoate, Progallin O, Stabilizer GA-8, 没食子酸辛酯 |
| molecular weight | 282.33 |
| Molecular formula | C15H22O5 |
| CAS | 1034-01-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble DMSO: 60 mg/mL (212.52 mM) |
| References | 1. Sales, SM , Roy, A , Antony, L , et al. Octyl gallate and gallic acid isolated from, Terminalia bellarica, regulates normal cell cycle in human breast cancer cell lines[J]. Biomedicine & Pharmacotherapy, 2018, 103:1577-1584. |