| Description | O-2050 is a high affinity cannabinoid CB 1 receptor antagonist with a K i of 2.5 nM. O-2050 inhibits cannabinoid CB 2 receptor with Ki of 0.2 nM. O-2050 decreased food intake in mice and caused locomotor stimulation in mice [1]. |
| In vivo | O-2050 (1, 3, 10, 30 mg/kg; ip; pretreatment 30 mins) produces significant and dose-dependent decreases in food intake in mice. O-2050 (10, 30 mg/kg) markedly causes locomotor stimulation [1]. |
| molecular weight | 417.56 |
| Molecular formula | C23H31NO4S |
| CAS | 1883545-42-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: <41.76 mg/mL Ethanol: <41.76 mg/mL |