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Norbormide

CAS No.: 991-42-4

Norbormide is a toxic compound used as a rodenticide. It has several mechanisms of action, acting as a vasoconstrictor a
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Description Norbormide is a toxic compound used as a rodenticide. It has several mechanisms of action, acting as a vasoconstrictor and calcium channel blocker.
Synonyms Mcneil 1025, S 6999, MCN 1025, Shoxin, Raticate
molecular weight 511.57
Molecular formula C33H25N3O3
CAS 991-42-4
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. D'Amore C, Orso G, Fusi F, Pagano MA, Miotto G, Forgiarini A, De Martin S, Castellani G, Ribaudo G, Rennison D, Brimble MA, Hopkins B, Ferrarese A, Bova S. An NBD Derivative of the Selective Rat Toxicant Norbormide as a New Probe for Living Cell Imaging. Front Pharmacol. 2016 Sep 23;7:315. eCollection 2016. PubMed PMID: 27721792; PubMed Central PMCID: PMC5034647. 2. Choi H, Conole D, Atkinson DJ, Laita O, Jay-Smith M, Pagano MA, Ribaudo G, Cavalli M, Bova S, Hopkins B, Brimble MA, Rennison D. Fatty Acid-Derived Pro-Toxicants of the Rat Selective Toxicant Norbormide. Chem Biodivers. 2016 Jun;13(6):762-75. doi: 10.1002/cbdv.201500241. Epub 2016 Jun 2. PubMed PMID: 27144301. 3. Rennison D, Laita O, Conole D, Jay-Smith M, Knauf J, Bova S, Cavalli M, Hopkins B, Linthicum DS, Brimble MA. Prodrugs of N-dicarboximide derivatives of the rat selective toxicant norbormide. Bioorg Med Chem. 2013 Sep 15;21(18):5886-99. doi: 10.1016/j.bmc.2013.06.071. Epub 2013 Jul 10. PubMed PMID: 23920483. 4. Rennison D, Laita O, Bova S, Cavalli M, Hopkins B, Linthicum DS, Brimble MA. Design and synthesis of prodrugs of the rat selective toxicant norbormide. Bioorg Med Chem. 2012 Jul 1;20(13):3997-4011. doi: 10.1016/j.bmc.2012.05.014. Epub 2012 May 15. PubMed PMID: 22658693.