| Description | NOD2 antagonist 1 (compound 32) is an effective and selective NOD2 antagonist (IC50: 5.23μM). NOD2 antagonist 1 in THP-1 cells repress Muramyl DiDP (MDP) -induced IL-8 secretion. NOD2 antagonist 1 in PBMCs cells inhibits MDP-induced elevation of IL-6, IL-10 and TNF-α. |
| molecular weight | 474.57 |
| Molecular formula | C26H26N4O3S |
| CAS | 2411441-54-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |