| Description | Nitidine is a bioactive plant benzophenanthridine alkaloid isolated from the root of Zanthoxylum nitidum. It shows anticancer, neuroprotective, antimalarial, anti-HIV, analgesic, anti-inflammatory and antifungal activities. |
| molecular weight | 348.37 |
| Molecular formula | C21H18NO4 |
| CAS | 6872-57-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 2.05 mg/mL (5.89 mM), Sonication is recommended. |
| References | 1. Khan H , Hadda T B , Touzani R . Diverse Therapeutic Potential of Nitidine, A Comprehensive Review[J]. Current Drug Metabolism, 2018. |
| Citations | 1. Chen F, Peng S, Li C, et al.Nitidine chloride inhibits mTORC1 signaling through ATF4-mediated Sestrin2 induction and targets IGF2R for lysosomal degradation.Life Sciences.2024: 122918. |