| Description | Niraxostat (Y-700) is one of the isocytosine derivatives as xanthine oxidase inhibitors. |
| Synonyms | Y 700, Y700, Y-700 |
| molecular weight | 299.32 |
| Molecular formula | C16H17N3O3 |
| CAS | 206884-98-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (167.05 mM) |
| References | 1. B-Rao C, et al. Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits. Bioorganic & Medicinal Chemistry, 2012, 20(9):2930-2939. 2. Atsushi Fukunari,et al. Y-700 [1-[3-Cyano-4-(2,2-dimethylpropoxy)phenyl]-1H-pyrazole-4-carboxylic acid]: a potent xanthine oxidoreductase inhibitor with hepatic excretion J Pharmacol Exp Ther . 2004 Nov;311(2):519-28. doi: 10.1124/jpet.104.070433. Epub 2004 Jun 9. 3. Takao Hashimoto,et al.Y-700, a novel inhibitor of xanthine oxidase, suppresses the development of colon aberrant crypt foci and cell proliferation in 1,2-dimethylhydrazine-treated mice Biosci Biotechnol Biochem . 2005 Jan;69(1):209-11 |