| Description | NIBR-17 is a pan class I PI3K inhibitor. NIBR-17 inhibits PI3KKα, PI3KKβ, PI3KKγ, and PI3KKδ with IC50 of 1 nM, 9.2 nM, 9 nM, and 20 nM respectively. |
| Target activity | PI3Kγ:9 nM, PI3Kα:1 nM, PI3Kβ:9.2 nM |
| molecular weight | 380.4 |
| Molecular formula | C18H20N8O2 |
| CAS | 944396-88-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/ml (144.58 mM) |