Description | NH2-C2-amido-C2-Boc is an alkyl/ether-based PROTAC linker employed in the synthesis of various PROTACs, including the PROTAC CDK2/9 Degrader-1[1]. NH2-C5-NH-Boc can also serve as a suitable precursor for the synthesis of these PROTACs. |
molecular weight | 216.28 |
Molecular formula | C10H20N2O3 |
CAS | 1692613-62-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
References | 1. Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2019 Dec 6;187:111952. |