| Description | NF546 (hydrate), a selective non-nucleotide P2Y11 agonist, exhibits a pEC50 value of 6.27 and induces interleukin-8 secretion from human monocyte-derived dendritic cells [1]. |
| In vitro | NF546（水合物）相对于P2Y1、P2Y2、P2Y4、P2Y6、P2Y12、P2X1、P2X2和P2X2-X3对P2Y11有较高的选择性。在人源单核细胞衍生的树突状细胞中，NF546（水合物）（100 μM；24小时）在刺激TSP-1释放和抑制LPS诱导的IL-12p70释放上具有等效功效[1]。 |
| molecular weight | 1424.01 |
| Molecular formula | C47H44N6Na4O17P4.13.5H2O |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |