| Description | Neurotensin TFA (39379-15-2 free base) is an endogenous 13 amino acid neuropeptide with profound opioid-independent analgesic effects. It behaves as a neurotransmitter in the brain, as a hormone in the gut, and also as a neuromodulator. It is implicated in the pathophysiology of several CNS disorders (including schizophrenia, Parkinson's disease, drug abuse, pain, cancer, inflammation, eating disorders, and central control of blood pressure) due to its association with a wide variety of neurotransmitter systems such as dopaminergic, sertonergic, glutamatergic, GABAergic, and cholinergic systems. It has a role as a human metabolite, a mitogen, a neurotransmitter and a vulnerary. |
| Synonyms | NEUROTENSIN TFA, Neurotensin TFA (39379-15-2 free base), 神经加压素 |
| molecular weight | 1786.98 |
| Molecular formula | C80H122F3N21O22 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 10 mM |
| References | 1. Feng YP, Wang J, Dong YL, Wang YY, Li YQ. The roles of neurotensin and its analogues in pain. Curr Pharm Des. 2015;21(7):840-8. doi: 10.2174/1381612820666141027124915. |