| Description | Neuraminidase-IN-13 (Compound 10), a neuraminidase inhibitor exhibiting antiviral activity, demonstrates significant inhibition of NDV infection in Vero cells with minimal cytotoxicity by impeding the release of viral particles from infected cells [1]. |
| In vitro | Neuraminidase-IN-13 在 NDV La Sota 菌株中展现出显著的抑制作用，能够有效抑制斑块形成，其 IC 50 值为 0.06 μM。同样，该化合物在抑制病毒增殖方面的 IC 50 为 0.04 μM，并且具有低毒性，CC 50 值大于2500 μM。此外，Neuraminidase-IN-13 能阻止病毒与 Vero 细胞结合，IC 50 为 4 μM，并能抑制病毒在 Vero 细胞中的释放，IC 50 值为 0.09 μM。 |
| molecular weight | 470.25 |
| Molecular formula | C13H13F7N4O7 |
| CAS | 2222067-23-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |