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NED-3238

CAS No.: 2389062-09-1

NED-3238 is a highly potent inhibitor of arginase I and II (IC50 of 1.3 nM and 8.1 nM, respectively).
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Description NED-3238 is a highly potent inhibitor of arginase I and II (IC50 of 1.3 nM and 8.1 nM, respectively).
Target activity Arginases I:1.3 nM , Arginase II:8.1 nM
molecular weight 349.23
Molecular formula C17H28BN3O4
CAS 2389062-09-1
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Van Zandt MC, et al. Discovery of N-Substituted 3-Amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic Acids as Highly Potent Third-Generation Inhibitors of Human Arginase I and II. J Med Chem. 2019 Aug 23.