| Description | NBD-557 is a potentially HIV-1 inhibitor. |
| Synonyms | N-(4-溴苯基)-N'-(2,2,6,6-四甲基哌啶-4-基)草酰胺 |
| molecular weight | 382.3 |
| Molecular formula | C17H24BrN3O2 |
| CAS | 333352-59-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 10 mg/mL (26.16 mM) |
| References | 1. Arne Schön, Madani N , Klein J C , et al. Thermodynamics of Binding of a Low-Molecular-Weight CD4 Mimetic to HIV-1 gp120 †[J]. Biochemistry, 2006, 45(36):10973-10980. 2. Curreli F , Kwon Y D , Zhang H , et al. Binding Mode Characterization of NBD Series CD4-Mimetic HIV-1 Entry Inhibitors by X-Ray Structure and Resistance Study[J]. Antimicrobial Agents and Chemotherapy, 2014, 58(9):5478-5491. |