| Description | NaV1.7 Blocker-801 is a potent NaV1.7 blocker. |
| molecular weight | 524.95 |
| Molecular formula | C20H15ClF2N6O3S2 |
| CAS | 1235403-75-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Huang J, Vanoye CG, Cutts A, Goldberg YP, Dib-Hajj SD, Cohen CJ, Waxman SG, George AL Jr. Sodium channel NaV1.9 mutations associated with insensitivity to pain dampen neuronal excitability. J Clin Invest. 2017 May 22. pii: 92373. doi: 10.1172/JCI92373. [Epub ahead of print] PubMed PMID: 28530638. 2. Sun H, Kollarik M, Undem BJ. Blocking voltage-gated sodium channels as a strategy to suppress pathological cough. Pulm Pharmacol Ther. 2017 May 15. pii: S1094-5539(17)30112-8. doi: 10.1016/j.pupt.2017.05.010. [Epub ahead of print] Review. PubMed PMID: 28522215. 3. Zhang X, Priest BT, Belfer I, Gold MS. Voltage-gated Na(+) currents in human dorsal root ganglion neurons. Elife. 2017 May 16;6. pii: e23235. doi: 10.7554/eLife.23235. PubMed PMID: 28508747; PubMed Central PMCID: PMC5433841. 4. Low SA, Robbins W, Tawfik VL. Complex management of a patient with refractory primary erythromelalgia lacking a SCN9A mutation. J Pain Res. 2017 Apr 27;10:973-977. doi: 10.2147/JPR.S129661. eCollection 2017. PubMed PMID: 28490900; PubMed Central PMCID: PMC5414616. |