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NAG-thiazoline

CAS No.: 179030-22-9

NAG-thiazoline (GlcNAc-thiazoline) is an O-GlcNAcase inhibitor with Ki value of 180 nM. It is active against V. campbell
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Description NAG-thiazoline (GlcNAc-thiazoline) is an O-GlcNAcase inhibitor with Ki value of 180 nM. It is active against V. campbellii with MIC value of 0.5 μM.
In vitro NGT 完全抑制了 V. campbellii 650 株的生长,最小抑菌浓度值为 0.5 μm[1]。
Target activity VhGlcNAcase:11.9 ± 1.0 μm
Synonyms GlcNAc-thiazoline, N-乙酰 - 葡糖胺基噻唑啉
molecular weight 219.26
Molecular formula C8H13NO4S
CAS 179030-22-9
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility DMSO: 55 mg/ml (250.84 mM)
References 1. NAG‐thiazoline is a potent inhibitor of the Vibriocampbellii GH20 β‐N‐Acetylglucosaminidase[J]. FEBS Journal, 2020.