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N4Py

CAS No.: 167695-87-6

N4Py is a good synthetic mimic of the Bleomycins (BLMs), which are a family of natural antibiotics used clinically in th
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Description N4Py is a good synthetic mimic of the Bleomycins (BLMs), which are a family of natural antibiotics used clinically in the treatment of certain cancers.
Synonyms N-4-Py, N 4 Py
molecular weight 367.45
Molecular formula C23H21N5
CAS 167695-87-6
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Geersing A, Ségaud N, van der Wijst MGP, Rots MG, Roelfes G. Importance of Metal-Ion Exchange for the Biological Activity of Coordination Complexes of the Biomimetic Ligand N4Py. Inorg Chem. 2018 Jun 19. doi: 10.1021/acs.inorgchem.8b00714. [Epub ahead of print] PubMed PMID: 29916702. 2. Chen PY, Tseng TH. A Switch from Mechanistic Competition Mediated by a Coordination between Temperature and Concentration Effects in the Oxidation Reaction of [FeII(N4Py/TPA)](OTf)2. Chemistry. 2018 Jun 11. doi: 10.1002/chem.201801028. [Epub ahead of print] PubMed PMID: 29889323. 3. Chen J, Unjaroen D, Stepanovic S, van Dam A, Gruden M, Browne WR. Selective Photo-Induced Oxidation with O(2) of a Non-Heme Iron(III) Complex to a Bis(imine-pyridyl)iron(II) Complex. Inorg Chem. 2018 Apr 16;57(8):4510-4515. doi: 10.1021/acs.inorgchem.8b00187. Epub 2018 Mar 30. PubMed PMID: 29601196; PubMed Central PMCID: PMC5906753. 4. Draksharapu A, Rasheed W, Klein JEMN, Que L Jr. Facile and Reversible Formation of Iron(III)-Oxo-Cerium(IV) Adducts from Nonheme Oxoiron(IV) Complexes and Cerium(III). Angew Chem Int Ed Engl. 2017 Jul 24;56(31):9091-9095. doi: 10.1002/anie.201704322. Epub 2017 Jun 27. PubMed PMID: 28598024; PubMed Central PMCID: PMC5598155.