| Description | N3-PEG6-Propanehydrazide is a polyethylene glycol (PEG) derived linker, specifically designed for use in the synthesis of proteolysis targeting chimeras (PROTACs) [1]. |
| In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| molecular weight | 393.44 |
| Molecular formula | C15H31N5O7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |