| Description | N-Methylpyrrolidone (1-Methyl-2-pyrrolidinone) (1-Methyl-2-pyrrolidinone) is a five-membered cyclic amide. N-Methylpyrrolidone is a widely used industrial organic polar solvent in the manufacture of adhesives, paints, fuels, and pharmaceuticals. |
| In vivo | N-methylpyrrolidone 在人类中引起皮肤刺激，并在大鼠中表现出致畸性。其生物降解的分子机制尚不明确。 |
| Synonyms | N-甲基吡咯烷酮, 1-Methyl-2-pyrrolidinone |
| molecular weight | 99.13 |
| Molecular formula | C5H9NO |
| CAS | 872-50-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 50 mg/mL (504.39 mM) |
| References | 1. Claudia Julieta Solís-González, et al. Novel Metabolic Pathway for N-Methylpyrrolidone Degradation in Alicycliphilus sp. Strain BQAppl Environ Microbiol. 2017 Dec 15;84(1):e02136-17. 2. Jing Wang, et al. Nitrate stimulation of N-Methylpyrrolidone biodegradation by Paracoccus pantotrophus: Metabolite mechanism and Genomic characterization. Bioresour Technol. 2019 Dec;294:122185. |