| Description | N-Methylisatoic anhydride is a 2'-OH selective acylation agent of RNAs. It is also widely used for resolving secondary RNA structures using the SHAPE technology. |
| Synonyms | NMIA, N-甲基靛红酸酐, 1-甲基苯唑 |
| molecular weight | 177.16 |
| Molecular formula | C9H7NO3 |
| CAS | 10328-92-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 60 mg/mL (338.68 mM) |
| References | 1. Ursuegui S, et al. Biotin-conjugated N-methylisatoic anhydride: a chemical tool for nucleic acid separation by selective 2'-hydroxyl acylation of RNA. Chem Commun (Camb). 2014 Jun 1;50(43):5748-51. |