| Description | N-acetyl Dapsone is an anti-inflammatory and antimicrobial compound widely used in the treatment of leprosy, malaria, acne and various immune disorders. |
| molecular weight | 290.34 |
| Molecular formula | C14H14N2O3S |
| CAS | 565-20-8 |
| Storage | store at low temperature,keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 30 mg/mL DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL DMF: 30 mg/mL |
| References | 1. Jarratt MT, et al. Safety and Pharmacokinetics of Once-Daily Dapsone Gel, 7.5% in Patients With Moderate Acne Vulgaris. J Drugs Dermatol. 2016;15(10):1250-1259. 2. Lemnge MM, et al. Simultaneous determination of dapsone, monoacetyldapsone and pyrimethamine in whole blood and plasma by high-performance liquid chromatography. J Chromatogr. 1993;613(2):340-346. 3. Carr K, et al. Simultaneous analysis of dapsone and monoacetyldapsone employing high performance liquid chromatography: a rapid method for determination of acetylator phenotype. Br J Clin Pharmacol. 1978;6(5):421-427. |